research technology and solutions
individualized medication guidance program
chemotherapy drug gene detection
through the detection of blood tumor chemotherapy drugs, the selection of appropriate drugs and doses, the optimization of clinical treatment programs to provide reference, and strive to accurately locate, accurate drug delivery, and ultimately achieve better therapeutic results.
cstb uses a generation of sequencing methods to detect blood tumor chemotherapy drugs, including 27 kinds of chemotherapy drugs such as tacrolimus, cyclosporine, fluorouracil, and ibidaxin, with high accuracy and high speed.
immunosuppressant blood concentration detection
through advanced pharmaceutical analysis methods to detect the concentration of drugs and their metabolites in the blood, combined with pharmacokinetic principles and data analysis, explore the range of blood drug concentrations, develop individualized drug delivery programs to improve efficacy (avoid or reduce toxic side effects) at the same time, it provides important evidence for the diagnosis and treatment of drug overdose and the patient's medication compliance, and finally achieves the purpose of safe, effective and rational drug use.
cstb used high performance liquid chromatography-mass spectrometry (hplc-ms) to detect the plasma concentrations of cyclosporine a, tacrolimus, sirolimus, and everolimus. the method requires small sample size, simple sample preparation, short detection time, strong specificity, high sensitivity, low detection limit and high accuracy, and quantitative analysis of various substances of biological matrix; data reporting speed and high accuracy ,high quality.
hcmv resistance mutation
through advanced pharmaceutical analysis methods to detect the concentration of drugs and their metabolites in the blood, combined with pharmacokinetic principles and data analysis, explore the range of blood drug concentrations, develop individualized drug delivery programs to improve efficacy (avoid or reduce toxic side effects) at the same time, it provides important evidence for the diagnosis and treatment of drug overdose and the patient's medication compliance, and finally achieves the purpose of safe, effective and rational drug use.
cstb uses nested pcr generation sequencing to detect mutations in hcmv ul97 and hcmv ul54 resistance genes, and the results are more accurate.
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